Innovating Treatments.
Transforming Lives.

Welcome to the Infectious Disease and Drug Discovery (IDDD) Lab at Texas Southern University—where groundbreaking science meets real-world impact. Our mission is to develop novel therapeutic solutions for global infectious diseases while advancing innovation in biomedical research.

Welcome to IDDD

Welcome to the Infectious Disease and Drug Discovery (IDDD) Lab at Texas Southern University, where groundbreaking science meets real-world impact. Our mission is to develop novel therapeutic solutions for global infectious diseases while advancing innovation in biomedical research.

Undergraduate research
fellowships open for 2025

The IDDD Lab at Texas Southern University is a leading research initiative focused on the discovery and development of new treatments for infectious diseases. As part of TSU’s College of Pharmacy and Health Sciences, we combine translational science, and training of the next generation of biomedical researchers.

Mission

To develop next-generation therapeutics targeting infectious diseases that disproportionately impact underserved communities.

Vision

To be a national hub for discovery and innovation in infectious disease research.

Meet the Principal Investigator

"At IDDD, we believe drug discovery should reflect the communities it serves. We are proud to lead cutting-edge research and inclusive training that advances science and social impact."

Dr. Omonike Olaleye, PI
Infectious Diseases and Drug Discovery (IDDD) Lab,
Senior Associate Vice President for Research and Innovation,
Texas Southern University

Research Focus Areas

Tuberculosis (TB)

Developing inhibitors for drug-resistant Mycobacterium tuberculosis.

HIV/AIDS

Novel integrase and protease inhibitors using molecular modeling

COVID-19 & Coronaviruses

Small molecule antivirals and spike protein neutralizers

Antimicrobial Resistance (AMR)

Investigating β-lactamase inhibitors and resistance mechanisms.

Quick Facts

Pubications

10+ peer-reviewed papers since 2020

Research

$7.8M in active research funding

Drug Discovery Platforms

Target Identification & Validation

Genomic and proteomic screening

High-Throughput Screening

50,000-compound library screening facility.

Computational Drug Design

AI-driven lead optimization and molecular docking.

Natural Products Chemistry

Isolating antimicrobial agents from local flora.

Our Facilities

Biocontainment Lab

BSL-2 with selective access for mycobacteria and viral assays

HTS Screening Core

Robotics-supported compound screening platform

Spectroscopy Suite

NMR

Computational Drug Discovery Lab

Molecular docking, pharmacophore modeling, and ADMET prediction, HPC

Partnerships & Collaborations

Institutional Collaborations

Organizational Collaborations

Collaborations with biotech startups on antiviral screening and formulation studies.

Community Partners

  • Local clinics providing isolates for AMR research
  • Public health outreach in underserved Houston neighborhoods

Join Our Lab

You're invited to join the Infectious Disease Drug Discovery and Development (IDDD) Lab at Texas Southern University! Our lab is a dynamic research initiative dedicated to discovering and developing innovative treatments for infectious diseases.
If you're passionate about making a difference in global health, we encourage you to explore our lab and consider joining our team. Together, let's advance scientific discovery and improve human health!